Project Information

Bid Title

ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

Issuing Agency

HEALTH AND HUMAN SERVICES, DEPARTMENT OF

Location

N/A

Published Date

Sep 21, 2026

Closing Date

Oct 7, 2026

Government Level

Federal

Status

Closed

Ref. #

ARPA-H-SOL-26-165

Original Source

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Bid Documents

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Project Description

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ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

Active

Contract Opportunity

Notice ID

ARPA-H-SOL-26-165

Related Notice

Department/Ind. Agency

HEALTH AND HUMAN SERVICES, DEPARTMENT OF

Sub-tier

NATIONAL INSTITUTES OF HEALTH

Office

ADVANCED RESEARCH PROJECTS AGENCY FOR HEALTH (ARPA-H)

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General Information View Changes

• Contract Opportunity Type: Solicitation (Updated)
• Updated Published Date: Sep 21, 2026 07:06 pm EDT
• Original Published Date: Sep 16, 2026 03:17 pm EDT
• Updated Date Offers Due: Oct 07, 2026 02:00 pm EDT
• Original Date Offers Due: Oct 07, 2026 02:00 pm EDT
• Inactive Policy: 15 days after date offers due
• Updated Inactive Date: Oct 22, 2026
• Original Inactive Date: Oct 22, 2026
• Initiative:
  • None

Classification

• Original Set Aside:
• Product Service Code: AN13 - HEALTH R&D SERVICES; HEALTH CARE SERVICES; EXPERIMENTAL DEVELOPMENT
• NAICS Code:
  • 541714 - Research and Development in Biotechnology (except Nanobiotechnology)
• Place of Performance:

Description View Changes

The Advanced Research Projects Agency for Health (ARPA-H) Comprehensive Organ System Modeling in Outer Space (COSMOS) Initiative aims to definitively prove or disprove if exposure to microgravity in Low Earth Orbit (LEO) truly accelerates tissue aging across brain, cardiac, uterine, and kidney tissue types and across several adult age brackets. Provided Tissue Aging Rate in Space (TARIS) exceeds Tissue Aging Rate on Earth (TAROE) at a rate that exceeds the on Earth breakeven cost for new drug R&D, COSMOS will create a first-in-class platform for fully autonomous, high-throughput drug screening in LEO that would be more cost effective and faster than new drug R&D on Earth.

ARPA-H anticipates multiple Other Transaction awards resulting from this announcement.

Interested parties are invited to download and review the attached COSMOS Innovative Solutions Opening (ISO) ARPA-H-SOL-26-165

Amendment 01 – 17 September 2026: This amendment includes updated hyperlinks and information on the updated Solutions summary portal.

Questions and Answers – 21 September 2026: This Q&A is provided for informational purposes only and does not amend the solicitation. All other questions are due by 23 September 2026 at 2:00PM ET.

Attachments/Links

Contact Information

Contracting Office Address

• 1301 K Street NW Suite 1200 West
• Washington , DC 20005
• USA

Primary Point of Contact

• COSMOS Team
• COSMOS@ARPA-H.GOV

Secondary Point of Contact

History

• Sep 21, 2026 07:06 pm EDTSolicitation (Updated)
• Sep 17, 2026 11:51 am EDT Solicitation (Updated)
• Sep 16, 2026 03:17 pm EDT Solicitation (Original)

Commodity Codes

• FSC AResearch and development

• NAICS 541714Research and Development in Biotechnology (except Nanobiotechnology)

Related bids

Sep 16, 2026	[Solicitation (Original)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
Sep 17, 2026	[Solicitation (Updated)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
Sep 23, 2026	[Solicitation (Updated)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
Sep 25, 2026	[Solicitation (Updated)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening
Oct 7, 2026	[Solicitation (Updated)] ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

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